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IMSR Site Hosted By: 
The International Mouse Strain Resource (IMSR) is funded by grant LM009693 from the National Library of Medicine (NLM) of the National Institutes of Health (NIH). Warranty Disclaimer & Copyright Notice Send questions and comments to IMSR. last database update August 27, 2010 IMSR 2.43 |
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We encourage you to participate with us in making this database as complete as possible for all worldwide mouse strain resources. If you or your institution hold mice, cryopreserved gametes or embryos, or ES cell lines that you distribute to other researchers, contributing information about them to the IMSR catalog will make them more widely known.
Contributing Strain Information to IMSR
To contribute data to the IMSR, there are three steps: register; correspond with the IMSR staff to set up scheduled submissions; begin submitting data.Registering
As the initial step in contributing data to the IMSR, a holder site must register by contacting the IMSR staff (imsr@informatics.jax.org) or by using our registration form.Setting Up For Submission
Once you have registered with the IMSR you will be contacted by the IMSR staff. We will need to finalize issues such as: your ability to comply with our recommended submission format; planning the frequency of your submissions; and other details surrounding the submission process.Submission Format
The IMSR accepts submissions as files in tab-delimited text format.- For each Strain ID - Strain Designation - Strain Type combination, there will be one or more lines in the file.
- If a Strain carries more than one mutation, each Mutation description, i.e., the set:
(Mutation Type - Chromosome - Gene Symbol - Gene Name - Allele Symbol - Allele Name) will require a separate line.
Column |
Description |
Example ** |
|---|---|---|
| Strain/Stock ID | The unique ID used by your site to represent this strain. | 4369 |
| Strain/Stock Designation | Full strain name. Superscripted portions of the name are enclosed in < >. For more information on nomenclature* of strain names see Mouse Nomenclature Guides. | C57BL/6J-Rag1<tm1Mom> Ins2<Akita>/J |
| Strain Type | Type of strain, comma-separated list. See below for the accepted list of strain types. | SEG, MSR |
| State | State in which the strain is held. Like strain type, if a strain is held in multiple states at a given site, it should be included as a comma-separated list. See below for strain state abbreviations. | LM,EM |
| MGI Allele Accession ID | This is the MGI Accession ID for the Allele. Use of this field should make providing allele symbol and name unnecessary. (Optional) | MGI:1857241 |
| Allele Symbol | Allele associated with this gene and strain. If a strain carries multiple alleles, a separate line is required for each. Please verify nomenclature* by searching MGI. | Rag1<tm1Mom> |
| Allele Name | Name of the Allele.(Optional, to aid in curation when symbol does not exist in MGI) | targeted mutation 1, Peter Mombaerts |
| Mutation Type | For each mutant allele, specifies the type of mutation that it represents. Usually there will be only one mutation type per Allele. Should there be an exception to this rule, these should be submitted as a comma-separated list. See below for mutation type abbreviations. | TM |
| Chromosome | Chromosome on which the Gene is located. | 2 |
| MGI Gene Accession ID | This is the MGI Accession ID for the Gene. Use of this field should make providing gene symbol and name unnecessary. (Optional) | MGI:97848 |
| Gene Symbol | Gene Symbol for mutation carried in this strain. If a strain carries multiple gene mutations, a separate line is required for each. Please verify nomenclature* by searching MGI. | Rag1 |
| Gene Name | Name of the Gene.(Optional, to aid in curation when symbol does not exist in MGI) | recombination activating gene 1 |
* Additional nomenclature assistance is available by emailing strains@informatics.jax.org.
** For this strain example (C57BL/6J-Rag1tm1Mom Ins2Akita/J), the submission file would include 2 lines. The first line is represented in the "Example" column above. Two lines (below) are required because two mutations are carried in this strain.
4369 C57BL/6J-Rag1<tm1Mom> Ins2<Akita>/J SEG,MSR LM,EM MGI:1857241 Rag1<tm1Mom> targeted mutation 1, Peter Mombaerts TM 2 MGI:97848 Rag1 recombination activating gene 1
4369 C57BL/6J-Rag1<tm1Mom> Ins2<Akita>/J SEG,MSR LM,EM MGI:1857572 Ins2<Akita> Akita SP 7 MGI:96573 Ins2 insulin II
Strain State Abbreviations(IMSR Glossary) |
|
|---|---|
| LM | live mouse |
| OV | cryopreserved ovaries |
| EM | cryopreserved embryos |
| SP | cryopreserved or freeze-dried sperm |
| ES | ES cell lines |
Strain Type Abbreviations(IMSR Glossary) |
|
|---|---|
| IS | inbred strain |
| SEG | segregating inbred strain |
| MSR | mutant strain |
| MSK | mutant stock |
| WDS | wild-derived inbred strain |
| COI | coisogenic strain |
| CON | congenic strain |
| CSS | consomic or chromosome substitution strain |
| RI | recombinant inbred (RI) |
| RC | recombinant congenic (RC) |
| MAH | major histocompatibility congenic |
| MIH | minor histocompatibility congenic |
| NON | noninbred stock |
| CCO | closed colony |
| UN | unclassified |
Mutation Type Abbreviations(IMSR Glossary) |
|
| SM | spontaneous mutation |
| TM | targeted mutation |
| TG | transgenic |
| GT | gene trap |
| CI | chemically induced mutation |
| RAD | radiation induced mutation |
| CH | chromosomal aberration |
| RB | Robertsonian translocation |
| TL | reciprocal translocation |
| TP | transposition |
| INV | inversion |
| INS | insertion |
| DEL | deletion |
| DP | duplication |
| OTH | other |